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Iboga-magnesium spray
- Development stage
- Preclinical
- Lead developer
- PsyLabs
- Modality
- Small Molecules
- Administration
- Atomized Spray
01
Overview
Iboga-magnesium spray is a plant-derived formulation developed by PsyLabs, a pharmaceutical-grade API manufacturer based in South Africa. The product combines extracts from the *Tabernanthe iboga* plant with magnesium, delivered through an atomized spray system. It is specifically designed for use in clinical trials, academic research, and psychedelic-assisted therapy. The primary active component, ibogaine, possesses a complex pharmacological profile, interacting with NMDA receptors, serotonin transporters, and opioid receptors, which has led to its investigation for treating substance use disorders and various psychiatric conditions. The inclusion of magnesium is likely intended to enhance the therapeutic effect or mitigate potential side effects, such as the QT interval prolongation associated with ibogaine.
- Other names
- Iboga + magnesium atomized sprayIboga-magnesium atomized spray
02
Targets
NMDAR (Glutamate receptor ionotropic, NMDA)KOR (Kappa opioid receptor)SERT (Sodium-dependent serotonin transporter)DAT (Dopamine plasma membrane transport protein)
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