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IBS-20

Development stage
Phase 2
Lead developer
Hong Kong Institute of Biotechnology
Administration
Oral
01

Overview

IBS-20 is a standardized Chinese herbal formulation composed of aqueous extracts from 20 different medicinal herbs. It is developed as a potential therapeutic agent for the treatment of irritable bowel syndrome (IBS). The formula is produced under good manufacturing practices (GMP), with each herb botanically and chemically authenticated. The mixture undergoes water extraction, concentration, and spray drying to yield a powder that is then formulated with water-soluble starch as an excipient. Chemical standardization uses liquid chromatography-mass spectrometry (LC-MS) with reference markers for quality assurance. The mechanism of action likely involves multiple pathways relevant to gastrointestinal function and inflammation, but specific molecular targets are not detailed in the available literature[1].

Other names
20-herb formulation20-herb Chinese medicine formula
02

Targets

IFNG (Interferon gamma)TNFA (Tumor necrosis factor alpha (soluble))IL1A (Interleukin 1 alpha)IL12B (Interleukin-12/23 p40 subunit)IL-6 (Interleukin 6)NOS2 (Nitric Oxide Synthase 2)

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