Drug intelligence / Profile preview

IBT-T03H

Development stage
Unknown
Lead developer
Integrated BioTherapeutics
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

**IBT-T03H** is a monoclonal antibody developed for the treatment of Marburg virus disease (MVD) and Ravn virus infection, two closely related filoviruses causing severe hemorrhagic fever. It has demonstrated protective efficacy in preclinical animal models against both Marburg and Ravn viruses. The program received a $16.3 million contract from NIAID in 2021 to support formulation and process development, preclinical safety studies, manufacturing, and a planned Phase 1 first-in-human dose-ranging clinical trial, highlighting its potential as a medical countermeasure for emerging infectious disease threats.[1][2][4][8]

02

Targets

PYG (Glycogen phosphorylase)

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