Drug intelligence / Profile preview

Ibupirac

Development stage
Phase 4
Lead developer
Roemmers
Modality
Small Molecules
Administration
Oral
01

Overview

**Ibupirac** is a branded formulation of **ibuprofen**, a non-steroidal anti-inflammatory drug (NSAID) marketed in countries such as Argentina and Uruguay for analgesic, anti-inflammatory, and antipyretic use.[2][3] Ibuprofen acts primarily through reversible inhibition of cyclooxygenase (COX-1 and COX-2) enzymes, leading to decreased synthesis of prostaglandins that mediate pain, inflammation, and fever.[1][5][7] Ibupirac products are used for mild to moderate pain (including headache, migraine, dental pain, dysmenorrhea, musculoskeletal and rheumatic pain), symptomatic relief of cold and flu, and reduction of fever in adults and pediatric patients, with various oral formulations (e.g., tablets, coated tablets, suspensions) tailored for general and specialized indications such as menstrual pain or musculoskeletal pain.[2][3][8][10][12]

Brand names
Ibupirac
Other names
ibuprofen
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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