ibuprofen + sodium bicarbonate

A fixed-dose **combination of ibuprofen and sodium bicarbonate**. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that acts as a non-selective inhibitor of cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), thereby reducing prostaglandin synthesis, leading to analgesic, anti-inflammatory, and antipyretic effects[6]. **Sodium bicarbonate** is an antacid that rapidly neutralizes stomach acid and raises gastric pH, which can enhance the dissolution and absorption of ibuprofen, providing faster onset of action[5]. Combination aims to provide rapid pain relief and address gastrointestinal discomfort or delay in absorption related to ibuprofen.