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ICAIT DC Vaccine (Prostate Cancer)
- Development stage
- Preclinical
- Lead developer
- ImmunoRestoration
- Modality
- Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Vaccines & Immunotherapeutics
- Administration
- Intranodal, Intralesional
01
Overview
ICAIT DC Vaccine (Prostate Cancer) is an autologous dendritic cell-based immunotherapy being developed by ImmunoRestoration for the treatment of prostate cancer. Utilizing the company's proprietary ICAIT™ (Immune Cell Activation and Immunotherapy Technology) platform, the vaccine consists of dendritic cells pulsed with HER-2 (Human Epidermal Growth Factor Receptor 2) antigens. The mechanism of action involves priming the patient's immune system to recognize and mount an adaptive immune response against HER-2-expressing tumor cells. As of early 2020, the candidate was in the preclinical stage of development, with the platform also being applied to several other HER-2 positive solid tumors.
- Other names
- ICAIT dendritic cell vaccine (Prostate Cancer)HER-2 pulsed dendritic cell vaccineHER2 pulsed dendritic cell vaccineHER 2 pulsed dendritic cell vaccine
02
Targets
pMHC (Peptide-MHC complex family)
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