Drug intelligence / Profile preview

Ichybum

Development stage
Unknown
Lead developer
Dermoscribe
Modality
Small Molecules
Administration
Topical
01

Overview

Ichybum is an over-the-counter (OTC) topical cream developed by Dermoscribe for the treatment of pruritus ani (chronic anal itching) and other perianal conditions. The formulation contains three active ingredients: 1% hydrocortisone, a corticosteroid that acts as a glucocorticoid receptor agonist to reduce inflammation, redness, and itching; 1% clioquinol, which provides broad-spectrum antibacterial and antifungal activity; and zinc oxide, which acts as a skin protectant. This combination is designed to address the multi-factorial nature of chronic anal itching, which often involves an inflammatory component and secondary microbial involvement. Ichybum is also indicated for the symptomatic relief of hemorrhoids and athlete's foot (tinea pedis).

Brand names
IchybumIchybum Anal Itching Cream
Other names
hydrocortisone + clioquinol + zinc oxide
02

Targets

GR (Glucocorticoid receptor)

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