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ICTCAR-TC
- Development stage
- Preclinical
- Lead developer
- Innovative Cellular Therapeutics
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
ICTCAR-TC is a preclinical-stage chimeric antigen receptor (CAR) T-cell therapy developed by SiDanSai Biotechnology (ICT) for the treatment of thyroid cancer. The therapy utilizes the company's proprietary CoupledCAR® platform, which is designed to enhance the expansion and infiltration of CAR-T cells into solid tumors. ICTCAR-TC specifically targets the Thyroid Stimulating Hormone Receptor (TSHR), a protein frequently overexpressed in thyroid malignancies. By leveraging the CoupledCAR® technology, the therapy aims to overcome the immunosuppressive microenvironment of solid tumors, potentially providing a more effective treatment option for patients with advanced thyroid cancer.
- Other names
- ICTCAR-TC (CoupledCAR®)
02
Targets
TSHR (Thyroid-stimulating hormone receptor)
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