Drug intelligence / Profile preview

IDB-011

Development stage
Phase 1
Lead developer
IDBiologics
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intramuscular
01

Overview

IDB-011 is an investigational **two-monoclonal-antibody combination** comprising IDB-774 and IDB-898, developed as a medical countermeasure against Rift Valley fever virus infection. The human antibodies bind distinct critical viral residues, directly neutralize Rift Valley fever virus replication, and have been engineered for extended half-life. The components are administered as separate consecutive intramuscular injections. IDB-011 is being evaluated in a randomized, placebo-controlled Phase 1 study in healthy adults for safety, tolerability, pharmacokinetics, and immunogenicity. ([idbiologics.com](https://idbiologics.com/pipeline))

Brand names
IDB-011IDB011IDB 011
Other names
IDB-774 + IDB-898

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