Drug intelligence / Profile preview

IDC005

Development stage
Preclinical
Lead developer
Prestige Biopharma
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

IDC005 is a first-in-class bispecific antibody being developed by Prestige Biopharma for the treatment of aggressive solid tumors, including pancreatic and ovarian cancers, as well as critical immune disorders. The therapeutic is designed to simultaneously target desmoplasia (the development of dense connective tissue) and both angiogenesis and lymph-angiogenesis (the formation of new blood and lymphatic vessels). By addressing these key features of the tumor microenvironment, IDC005 aims to inhibit tumor growth and metastasis in highly aggressive cancers. It is currently in the preclinical stage of development with proof-of-concept established.

02

Targets

VEGFR4 (Vascular endothelial growth factor Receptor-3)

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