Drug intelligence / Profile preview

IDC007

Development stage
Preclinical
Lead developer
Prestige Biopharma
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

IDC007 is a preclinical-stage bispecific antibody being developed by Prestige Biopharma for the treatment and prevention of Cytokine Release Syndrome (CRS). CRS is a systemic inflammatory response characterized by a massive release of cytokines, often triggered by immunotherapies such as CAR-T cell therapies and immune checkpoint inhibitors, or by severe infectious diseases like COVID-19. IDC007 is engineered to simultaneously target and suppress two key molecules involved in the cytokine cascade, aiming to provide a more comprehensive mitigation of the inflammatory storm than single-target therapies. The drug is currently in the cell line development phase at Prestige Biopharma's Innovative Discovery Centre (IDC) in Busan, South Korea.

02

Targets

IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))

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