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IDC008
- Development stage
- Preclinical
- Lead developer
- Prestige Biopharma Innovative Discovery Centre
- Modality
- Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
IDC008 is an investigational bispecific antibody being developed by Prestige Biopharma for the treatment of solid tumors. It is designed to simultaneously target Pancreatic Adenocarcinoma Up-regulated Factor (PAUF) and an undisclosed immune checkpoint molecule. PAUF is a pro-oncogenic factor that contributes to an immunosuppressive tumor microenvironment, often leading to resistance against standard immune checkpoint inhibitors. By dual-targeting PAUF and a checkpoint molecule, IDC008 aims to reduce off-target effects and enhance the selectivity and efficacy of the immune response within the tumor microenvironment. The drug is currently in the preclinical stage of development.
02
Targets
PAUF (Pancreatic adenocarcinoma upregulated factor)
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