Drug intelligence / Profile preview

IDC2503

Development stage
Preclinical
Lead developer
Prestige Biopharma Innovative Discovery Centre
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

IDC2503 is a preclinical-stage monoclonal antibody biosimilar being developed by Prestige Biopharma (PBK). It is designed as a biosimilar to atezolizumab (marketed as Tecentriq), a humanized monoclonal antibody that targets programmed death-ligand 1 (PD-L1). By inhibiting the interaction between PD-L1 and its receptors, PD-1 and B7.1, IDC2503 acts as an immune checkpoint inhibitor, preventing the suppression of T-cell-mediated immune responses against tumor cells. The drug is currently in preclinical development for the treatment of non-small cell lung cancer (NSCLC) and urothelial carcinoma, aiming to provide a therapeutic profile similar to the reference product.

Other names
atezolizumab biosimilar
02

Targets

CD274 (Programmed cell death protein 1 ligand 1)

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