Drug intelligence / Profile preview

IDF190400338

Development stage
Preclinical
Lead developer
IlDong Pharmaceutical Co Ltd
Modality
Small Molecules
Administration
Oral
01

Overview

IDF190400338 is a small-molecule dual modulator of the adenosine A1 and A2A receptors being developed by Ildong Pharmaceutical and its R&D subsidiary, Yunovia, for the treatment of Parkinson's disease. Adenosine receptors are integral to the modulation of dopaminergic signaling within the basal ganglia, a key area affected in Parkinson's disease. By targeting both the A1 and A2A receptor subtypes, the compound aims to improve motor function and potentially offer neuroprotective effects. The drug is currently in the preclinical stage, specifically undergoing IND-enabling studies to support future clinical trials.

Other names
Ildong A1/A2A receptor modulator
02

Targets

ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)

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