Drug intelligence / Profile preview

IDOV-Immune + AntiAngio

Development stage
Preclinical
Lead developer
ViroMissile
Modality
Oncolytic Viruses → Oncolytic Therapeutics, Gene Therapies
Administration
Intravenous
01

Overview

IDOV-Immune + AntiAngio is a preclinical-stage engineered oncolytic virus (gene therapy) candidate being developed by ViroMissile in collaboration with Longyao Biotech. Built on the proprietary IDOV™ (Intravenously Deliverable Oncolytic Virus) platform, which utilizes a genetically engineered vaccinia virus backbone, this therapy is designed for systemic intravenous delivery to target tumors throughout the body. It combines two distinct therapeutic mechanisms: immune enhancement to stimulate robust anti-tumor immune responses, and anti-angiogenesis to target and inhibit tumor blood vessel formation. This dual-action approach is intended to support direct oncolytic activity while simultaneously restricting tumor angiogenesis, offering a comprehensive strategy for the treatment of solid tumors.

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