Drug intelligence / Profile preview

IDP-004

Development stage
Preclinical
Lead developer
InduPro
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

IDP-004 is a bispecific antibody-drug conjugate (ADC) being developed by InduPro Therapeutics for the treatment of solid tumors. It is designed to simultaneously target MET (Hepatocyte Growth Factor Receptor) and a proprietary Tumor Associated Proximity Antigen-M1 (TAPA-M1). By leveraging InduPro's proximity biology platform, the drug aims to deliver a cytotoxic payload specifically to cancer cells where these two antigens are in close proximity, potentially improving the therapeutic index and overcoming resistance mechanisms associated with MET-targeted therapies. The drug is currently in the lead optimization stage of preclinical development.

02

Targets

MET (Mesenchymal-epithelial transition factor receptor)TAPA-M1 (Tumor associated proximity Antigen-M1)

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