Drug intelligence / Profile preview

iferanserin

Development stage
Discontinued
Lead developer
Ventrus Biosciences
Modality
Small Molecules
Administration
Rectal
01

Overview

Iferanserin is a small molecule drug that acts as a selective antagonist of the serotonin 5-HT2A receptor. It was developed primarily as an intra-rectal formulation for the treatment of hemorrhoid disease. The drug reached phase III clinical trials for this indication but development has since been discontinued. Iferanserin was initially developed by Assembly Biosciences and investigated in both the United States and Germany for internal hemorrhoids.

Other names
iferanserin [INN]58754-46-4NWR3BEB8PANWR-3BEB8PANWR 3BEB8PA
02

Targets

HTR2A (Serotonin receptor 5-HT2A)

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