Drug intelligence / Profile preview

ifosfamide + gemcitabine

Development stage
Phase 2
Lead developer
NuGen Medical Devices
Modality
Small Molecules
Administration
Intravenous
01

Overview

A combination chemotherapy regimen consisting of ifosfamide (an alkylating agent) and gemcitabine (a nucleoside analog). This combination works through complementary mechanisms to inhibit DNA synthesis and cell division, showing synergistic effects against cancer cells. It is primarily used as salvage therapy in patients with relapsed or refractory malignancies.

Other names
Gemcitabine and IfosfamideGemcitabine plus Ifosfamide
02

Targets

RNR (Ribonucleotide reductase)DNA

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