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IG3018 is an oral small molecule drug under development by Intelligem Therapeutics Australia for the treatment of hyperuricemia, including in patients with or without chronic kidney disease. It belongs to the class of uricosurics, which are drugs that increase the excretion of uric acid in urine to lower blood uric acid levels. The precise mechanism of action for IG3018 has not been defined publicly. As of early 2025, it is being evaluated in phase I/II clinical trials for safety, tolerability, pharmacokinetics (PK), and efficacy in subjects with hyperuricemia and those with advanced predialysis chronic kidney disease (CKD stages 3a–4)[1][2][3][4][5][6][7].
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