Drug intelligence / Profile preview

Iglu

Development stage
Unknown
Lead developer
Diomed Developments
Modality
Small Molecules
Administration
Topical
01

Overview

Iglu is an over-the-counter (OTC) topical treatment specifically formulated for the management of mouth ulcers (aphthous ulcers). Developed and marketed by the Diomed Group (through its subsidiary Dermal Laboratories), the product is typically available as a bioadhesive gel. Its primary active ingredients are lidocaine hydrochloride, a local anesthetic that provides rapid pain relief by blocking sodium channels, and aminoacridine hydrochloride, an antiseptic that helps prevent secondary bacterial infection of the ulcerated tissue. A key feature of the Iglu formulation is its water-resistant, bioadhesive property, which allows the gel to form a physical protective barrier over the ulcer. This shield protects the sensitive area from further irritation by food, drink, or saliva, thereby facilitating the natural healing process.

Brand names
IgluIglu GelIglu Rapid Relief Gel
Other names
lidocaine hydrochloride + aminoacridine hydrochloride
02

Targets

IGF-1 (Insulin-like growth factor 1)EGFR T790M (Epidermal growth factor receptor T790M mutant)CASP3 (Caspase-3)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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