Drug intelligence / Profile preview

IGN001

Development stage
Unknown
Lead developer
ImmunGene
Modality
Ligand-Fc Fusions → Fc Fusion Proteins → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

IGN001 is an antibody-interferon fusion protein developed by ImmunGene, Inc., designed to treat various cancers by leveraging antibody-directed delivery of interferon to enhance antitumor activity through immune-mediated cytotoxicity. It belongs to a series of similar candidates (IGN002, IGN003) that were outlicensed and later regained by ImmunGene in 2013 from Valor Biotherapeutics. Limited public data exists on its specific mechanism, targets, clinical trials, or current status, suggesting it is an early preclinical or development-stage asset focused on oncology.

02

Targets

ERBB2 (Erb-b2 receptor tyrosine kinase 2)IFNAR (Immune system modulation via type I interferon receptor)

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