Drug intelligence / Profile preview

IgY-110

Development stage
Preclinical
Lead developer
IGY Immune Technologies & Life Sciences
Modality
Recombinant Proteins and Enzymes, Antibody-Based Therapeutics
Administration
Intranasal
01

Overview

IgY-110 is a polyclonal IgY antibody preparation targeting the spike proteins of SARS-CoV-2, developed primarily as an intranasal spray for the prevention and treatment of COVID-19 and other coronavirus infections.[4][5][7][9] Generated in hens and purified from egg yolks, the IgY antibodies bind and neutralize the viral spike protein, blocking its interaction with the ACE2 receptor and thereby preventing viral entry into host cells.[3][4][5] IGY Life Sciences is developing IgY-110 with a focus on high-risk populations such as the elderly and immunocompromised, leveraging the established GRAS safety status and mucosal delivery to provide rapid, localized passive immunity in the upper respiratory tract.[4][5][10]

02

Targets

RBD (SARS-CoV-2 spike receptor-binding domain)

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