Drug intelligence / Profile preview

IHS002

Development stage
Unknown
Lead developer
Wuxi Huatai Innovative Pharmaceutical Technology Research Institute
Modality
Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

IHS002 is a recombinant human acidic fibroblast growth factor (rh-aFGF) developed by Wuxi Huatai Innovative Drug Technology Research Institute. As a potent mitogen, it stimulates the proliferation and migration of various cell types essential for tissue repair, including fibroblasts, vascular endothelial cells, and keratinocytes. By binding to and activating fibroblast growth factor receptors (FGFRs), IHS002 promotes angiogenesis and accelerates the healing of both acute and chronic wounds. The drug is primarily being investigated for the treatment of deep second-degree burns, diabetic foot ulcers, and pressure ulcers, and is typically administered as a topical gel or solution.

Other names
recombinant human acidic fibroblast growth factorrh-aFGF
02

Targets

FGFR3 (Fibroblast growth factor receptor 3)FGFR1 (Fibroblast growth factor receptor 1)FGFR4 (Fibroblast growth factor receptor 4)FGFR2 (Keratinocyte growth factor receptor)

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