IL13Ra2 shRNA

IL13Ra2 shRNA is a research-stage molecular tool utilizing short hairpin RNA (shRNA) to silence the expression of the Interleukin-13 Receptor Alpha 2 (IL13Ra2) gene via RNA interference (RNAi). IL13Ra2 is a high-affinity decoy receptor for IL-13 that is overexpressed in various malignancies, including glioblastoma multiforme (GBM), pancreatic cancer, and non-small cell lung cancer (NSCLC). In preclinical models, knockdown of IL13Ra2 using shRNA has been shown to inhibit tumor cell migration, invasion, and adhesion, suggesting its potential as a therapeutic target. These shRNA constructs are typically delivered via viral vectors (lentiviral or retroviral) and are primarily used in laboratory settings to study gene function and oncogenic pathways.

Other names

IL13RA2 shRNAIL-13RA2 shRNAIL 13RA2 shRNAInterleukin-13 receptor alpha 2 short hairpin RNAInterleukin13 receptor alpha 2 short hairpin RNAInterleukin 13 receptor alpha 2 short hairpin RNA