Drug intelligence / Profile preview

illicium verum extract

Development stage
Preclinical
Administration
Oral, Inhalation, Topical
01

Overview

Illicium verum extract is derived from the fruit of Illicium verum, also known as Chinese star anise, a medium-sized evergreen tree native to South China and northeast Vietnam. The extract—typically obtained from the fruit or seeds—contains numerous bioactive compounds, notably trans-anethole (a major aromatic component), shikimic acid, flavonoids, phenylpropanoids, lignans, and sesquiterpenoids[1][2][5][6]. Traditionally, it has been used in both medicine and food, especially in Asia, for ailments such as respiratory infections, digestive problems, colic, and coughs[3][4]. Modern pharmacological studies support a range of bioactivities, including anti-inflammatory, antioxidant, antibacterial, antifungal, antispasmodic, and possible anti-obesity effects[1][2][6]. Shikimic acid from Illicium verum is an industrial precursor for synthesis of the antiviral drug oseltamivir (Tamiflu), although the extract itself is not a proven antiviral[1][2][3]. The extract is widely used in traditional medicine, food, cosmetics, and perfumery[1][2][5]. Concerns exist regarding contamination with toxic species like Japanese star anise (Illicium anisatum), which can cause neurotoxicity[1][3][4][5].

Other names
illicium verum extractstar anise extractstar anise oilChinese star anise extractbadian extract
02

Targets

NF-κBIL1B (Interleukin-1 beta)IL-6 (Interleukin 6)

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