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Illicium verum extract is derived from the fruit of Illicium verum, also known as Chinese star anise, a medium-sized evergreen tree native to South China and northeast Vietnam. The extract—typically obtained from the fruit or seeds—contains numerous bioactive compounds, notably trans-anethole (a major aromatic component), shikimic acid, flavonoids, phenylpropanoids, lignans, and sesquiterpenoids[1][2][5][6]. Traditionally, it has been used in both medicine and food, especially in Asia, for ailments such as respiratory infections, digestive problems, colic, and coughs[3][4]. Modern pharmacological studies support a range of bioactivities, including anti-inflammatory, antioxidant, antibacterial, antifungal, antispasmodic, and possible anti-obesity effects[1][2][6]. Shikimic acid from Illicium verum is an industrial precursor for synthesis of the antiviral drug oseltamivir (Tamiflu), although the extract itself is not a proven antiviral[1][2][3]. The extract is widely used in traditional medicine, food, cosmetics, and perfumery[1][2][5]. Concerns exist regarding contamination with toxic species like Japanese star anise (Illicium anisatum), which can cause neurotoxicity[1][3][4][5].
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