Drug intelligence / Profile preview

Illuminate Cream

Development stage
Phase 2
Lead developer
Olympia Pharmaceuticals
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

Illuminate Cream refers to several distinct topical dermatological products marketed under the "Illuminate" or "Illuminate Rx" names. These creams are designed for skin brightening, anti-aging, and treatment of hyperpigmentation. The formulations vary by manufacturer: - **Olympia Pharmaceuticals' Illuminate** is a compounded cream available in three tiers (Base, Plus, Max), containing retinoic acid (0.05%), hyaluronic acid (0.1–0.2%), ascorbic acid (2%), and in the Max version also hydroquinone (8%). It targets wrinkles, fine lines, sun damage, acne scars, and hyperpigmentation by promoting cell turnover (retinoic acid), hydrating skin (hyaluronic acid), providing antioxidant protection and brightening effects (ascorbic acid), and inhibiting melanin production for pigment correction in the Max formula with hydroquinone[1]. - **KaramMD Skin's Illuminate Anti-Aging Cream** is an all-in-one formula featuring encapsulated slow-release retinol for gentle exfoliation and wrinkle reduction; niacinamide to even skin tone; peptide complex for repair; sodium hyaluronate for hydration; botanical lighteners; antioxidants like vitamins C & E; squalene; edelweiss flower extract; hibiscus flower extract; jojoba oil and shea butter[5][6]. This product focuses on anti-aging benefits—smoothing fine lines/wrinkles—and improving overall radiance. - **Kirsch Dermatology's Illuminate Rx** uses cysteamine 5% as its primary active ingredient to lighten dark spots/hyperpigmentation by inhibiting melanin synthesis[2][3]. It also contains soothing agents such as aloe vera along with various plant oils. All versions are intended for topical use on the face/neck to address uneven pigmentation or signs of aging.

Brand names
Illuminate CreamIlluminateIlluminate Rx
Other names
Olympia IlluminateKaramMD Illuminate Anti-Aging CreamKirsch Dermatology Illuminate Rx
02

Targets

TYR (Tyrosinase)TYRP1 (Tyrosinase-related protein 1)

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