ilodecakin

Ilodecakin is a recombinant form of human interleukin‑10 (IL‑10), often developed in a pegylated formulation (pegilodecakin). It acts as an immunotherapy and anti-inflammatory agent by replacing or mimicking endogenous IL‑10, a cytokine with potent anti-inflammatory and immunoregulatory properties. Ilodecakin has been investigated for use in inflammatory disorders, Crohn's disease, rheumatoid arthritis, solid tumors (including pancreatic cancer), wound healing, and scar tissue reduction. Its mechanism involves modulation of immune responses through the IL‑10 receptor pathway to suppress pro-inflammatory cytokines and promote tissue repair[1][3][5].

Brand names

Tenovil

Other names

human interleukin 10 recombinant E. coliinterleukin 10 ilodecakininterleukin10 ilodecakininterleukin-10 ilodecakinPEGylated human IL‑10PEGylated recombinant human Interleukin‑10