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ILT1
- Development stage
- Preclinical
- Lead developer
- Lineage Cell Therapeutics
- Modality
- Allogeneic CAR-T → CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Allogeneic iPSCs → iPSCs → Pluripotent Stem Cells → Stem Cell Therapies → Cell Therapies
01
Overview
ILT1 is an allogeneic islet cell therapy program being developed by Lineage Cell Therapeutics for the treatment of Type 1 Diabetes (T1D). The program focuses on the large-scale production of functional islet cells—pancreatic cells responsible for secreting hormones such as insulin and glucagon—using a proprietary dynamic culturing system. By leveraging its manufacturing capabilities, Lineage aims to overcome commercialization hurdles associated with traditional islet cell therapies. Future development plans include demonstrating compatibility with hypo-immune cell lines to potentially eliminate the need for chronic immunosuppression in clinical T1D applications.
- Other names
- ILT1-Lineage Cell Therapeutics-cell therapy-Type 1 DiabetesILT-1-Lineage Cell Therapeutics-cell therapy-Type 1 DiabetesILT 1-Lineage Cell Therapeutics-cell therapy-Type 1 Diabetes
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