Drug intelligence / Profile preview

Imescard

Development stage
Unknown
Lead developer
Hospital de Clínicas de Porto Alegre
Modality
Small Molecules
Administration
Rectal, Oral
01

Overview

Imescard is a topical antihemorrhoidal combination therapy primarily marketed in Brazil. It is formulated as an ointment containing epinephrine (adrenalin), hamamelis (witch hazel) extract, and water smartweed (*Polygonum punctatum*) extract. The drug functions through multiple mechanisms: epinephrine acts as a potent vasoconstrictor to reduce swelling and bleeding; hamamelis provides astringent properties that help shrink swollen tissue and soothe irritation; and water smartweed extract contributes anti-inflammatory and hemostatic effects. It is indicated for the symptomatic relief of hemorrhoidal disease, including pain, inflammation, and bleeding.

Brand names
Imescard
Other names
Imescard ointmentImescard composto
02

Targets

ADRA1A (α1A)ADRA2A (α2A)ADRB2 (β2)ADRB1 (β1)

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