Drug intelligence / Profile preview

immortelle extract

Development stage
Preclinical
Lead developer
Viola Pharm
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Immortelle extract is a botanical product derived from the flowers and aerial parts of *Helichrysum italicum*. The extract contains essential oils rich in compounds such as **neryl acetate**, **α-pinene**, **nerol**, **geranyl acetate**, and diverse sesquiterpenes and flavonoids[2][4][6]. It exhibits **choleretic (stimulates bile flow)**, **anti-inflammatory**, **antioxidant**, **antimicrobial**, **antispasmodic**, and **wound-healing** activities. Neryl acetate, the most abundant active molecule (up to ~42% in essential oil), is noted for stimulating epidermal cell differentiation and ceramide synthesis, supporting the skin barrier[4]. Immortelle extract is used topically for skin repair, anti-aging, and healing wounds, and orally/traditionally for supporting liver and gallbladder function, digestion, and immune health[1][3][5]. In vitro and in vivo research confirm antibacterial, anti-inflammatory, and tissue-repair effects, but clinical evidence for oral indications remains limited[1][5]. The extract is widely utilized in dietary supplements, herbal preparations, and cosmeceuticals.

Brand names
Helichrysum Italicum Flower Oil
Other names
immortelle essential oilItalian helichrysum essential oilHelichrysum italicum extract
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)

Beyond the preview

Go deeper on immortelle extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on immortelle extract.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call