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Immortelle extract is a botanical product derived from the flowers and aerial parts of *Helichrysum italicum*. The extract contains essential oils rich in compounds such as **neryl acetate**, **α-pinene**, **nerol**, **geranyl acetate**, and diverse sesquiterpenes and flavonoids[2][4][6]. It exhibits **choleretic (stimulates bile flow)**, **anti-inflammatory**, **antioxidant**, **antimicrobial**, **antispasmodic**, and **wound-healing** activities. Neryl acetate, the most abundant active molecule (up to ~42% in essential oil), is noted for stimulating epidermal cell differentiation and ceramide synthesis, supporting the skin barrier[4]. Immortelle extract is used topically for skin repair, anti-aging, and healing wounds, and orally/traditionally for supporting liver and gallbladder function, digestion, and immune health[1][3][5]. In vitro and in vivo research confirm antibacterial, anti-inflammatory, and tissue-repair effects, but clinical evidence for oral indications remains limited[1][5]. The extract is widely utilized in dietary supplements, herbal preparations, and cosmeceuticals.
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