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Immucothel + Montanide
- Development stage
- Unknown
- Lead developer
- Biosyn
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Subcutaneous
01
Overview
Immucothel + Montanide is an investigational vaccine combination consisting of a low molecular weight Keyhole Limpet Hemocyanin (KLH) protein (Immucothel) and the oil-based adjuvant Montanide ISA 51. Developed by the National Institute of Allergy and Infectious Diseases (NIAID) in collaboration with the Immune Tolerance Network, this combination is used as a tool to evaluate the induction of oral tolerance and the strength of immune responses in the context of autoimmune disorder research. Immucothel serves as a neoantigen to challenge the immune system, while Montanide ISA 51 enhances the resulting immune response to ensure it is measurable. The combination is typically administered subcutaneously in clinical pilot studies to healthy volunteers before testing in patients with specific autoimmune conditions.
- Other names
- Immucothel + Montanide ISA 51KLH + Montanide ISA 51
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