ImmunD

ImmunD is a pharmaceutical brand of cholecalciferol (Vitamin D3), a fat-soluble secosteroid essential for maintaining calcium and phosphate homeostasis. It is primarily indicated for the treatment and prevention of Vitamin D deficiency, osteoporosis, and related bone disorders. Cholecalciferol acts as a prohormone that is metabolically converted to its active form, calcitriol (1,25-dihydroxyvitamin D3), through sequential hydroxylations in the liver and kidneys. Calcitriol functions as a high-affinity ligand for the Vitamin D Receptor (VDR), a nuclear transcription factor. Upon activation, the VDR-calcitriol complex modulates the expression of genes involved in intestinal calcium absorption, renal calcium handling, and bone remodeling. Additionally, ImmunD plays a significant role in immune modulation by enhancing the antimicrobial activities of innate immune cells and regulating adaptive immune responses.

Brand names

ImmunD

Other names

cholecalciferolVitamin D3calciol