Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
IMOD
- Development stage
- Phase 3
- Lead developer
- ParsRus Research Group
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Intravenous, Oral
01
Overview
IMOD (brand name Setarud) is a multiherbal immunomodulating drug developed by the ParsRus Research Group. It is a botanical formulation composed of *Urtica dioica* (stinging nettle) extract, carotenoids, urea, and selenium. The drug acts by suppressing the production of pro-inflammatory cytokines, specifically Tumor Necrosis Factor alpha (TNF-α), Interferon-gamma (IFN-γ), and Interleukin-2 (IL-2). IMOD has been primarily investigated for the treatment of severe sepsis, where it has demonstrated efficacy in reducing mortality and improving clinical severity scores such as SAPS, SOFA, and APACHE. Additionally, it has been studied for its potential in managing HIV/AIDS by improving CD4+ T-cell counts, as well as for ulcerative colitis and type 1 diabetes.
- Brand names
- Setarud
- Other names
- Setarud
02
Targets
IFNG (Interferon gamma)IL-2 (Interleukin 2)TNFA (Tumor necrosis factor alpha (soluble))
Beyond the preview
Go deeper on IMOD.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on IMOD.