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IMPACT Immunonutrition (brand name: Nestlé IMPACT Advanced Recovery) is an oral enteral immunonutrition formula developed by Nestlé Health Science. It is classified as an immune-modulating, nutrient-enriched formula containing a specific blend of arginine, omega-3 polyunsaturated fatty acids (PUFAs), nucleotides, and antioxidants such as selenium. The product is designed to modulate the immune and inflammatory systems, thereby reducing the risk of postoperative infectious complications and shortening hospital stays. It is primarily used perioperatively in patients undergoing major elective surgeries, including gastrointestinal, cardiac, and orthopedic procedures. The formula has been evaluated in clinical trials, such as the PINT trial (NCT03333148), for its ability to improve surgical outcomes in specific populations like those with Inflammatory Bowel Disease (IBD).
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