Drug intelligence / Profile preview

IN-003

Development stage
Preclinical
Lead developer
Inhalon Biopharma
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Inhalation
01

Overview

**IN-003** is an Inhalon Biopharma preclinical inhaled antibody program for treatment of human metapneumovirus infection. The product is reported to comprise two potent neutralizing monoclonal antibodies directed against the human metapneumovirus fusion protein. It is designed for delivery to the airways using Inhalon’s muco-trapping platform, in which antiviral antibodies bind respiratory virions and crosslink them to airway mucins, limiting viral access to epithelial cells and promoting clearance through normal mucociliary transport. The underlying hMPV antibodies originated from work at the University of Georgia and were licensed to Inhalon for development. ([sbir.gov](https://www.sbir.gov/portfolio/2666337))

Other names
IN 003IN003IN-003
02

Targets

HMPV F (Human metapneumovirus fusion protein)

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