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inactivated COVID-19 vaccine (Vero cells)
- Development stage
- Phase 1
- Lead developer
- Beijing Institute of Biological Products
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Inactivated COVID-19 vaccine (Vero cells) refers to a class of vaccines developed using traditional inactivated virus technology. The process involves culturing the SARS-CoV-2 virus in Vero cells (African green monkey kidney cells), followed by inactivation using β-propiolactone to ensure the virus cannot replicate while maintaining its antigenic integrity. These vaccines are typically formulated with an aluminum hydroxide adjuvant to enhance the immune response. Major examples include the vaccines developed by Sinopharm's Beijing Institute of Biological Products (COVILO) and Sinovac Biotech (CoronaVac). These vaccines have been widely used globally and received Emergency Use Listing (EUL) from the World Health Organization for the prevention of COVID-19 in various age groups.
- Brand names
- COVILOCoronaVacHayat-Vax
- Other names
- Sinopharm COVID-19 vaccineSinovac COVID-19 vaccineSARS-CoV-2 Vaccine (Vero Cell), InactivatedBIBP-CorV
02
Targets
E (Tick-borne encephalitis virus envelope protein)M protein (SARS-CoV-2 membrane protein)N (Nucleocapsid protein)SARS-CoV-2 spike
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