Drug intelligence / Profile preview

inactivated enterovirus 71 vaccine + measles attenuated live vaccine

Development stage
Unknown
Lead developer
Chinese Academy of Medical Sciences
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The **inactivated enterovirus 71 vaccine + measles attenuated live vaccine** refers to a combination immunization regimen or potential combination vaccine product consisting of an inactivated Enterovirus 71 (EV71) vaccine and a live attenuated measles vaccine. The EV71 component, specifically the inactivated vaccine developed by the Institute of Medical Biology at the Chinese Academy of Medical Sciences (IMBCAMS) using human diploid cells (KMB-17), is designed to prevent hand, foot, and mouth disease (HFMD) and its associated neurological complications. The measles component is a live attenuated virus vaccine intended to provide immunity against measles. Clinical studies, including Phase 4 trials, have evaluated the safety and immunogenicity of co-administering these vaccines at the same time point in infants (typically 8 months of age) to simplify the pediatric immunization schedule without compromising the protective efficacy of either component.

Brand names
Inlive
Other names
EV71 + measles attenuated live vaccineinactivated Enterovirus 71 vaccine and measles attenuated live vaccine co-administrationEV71 vaccine + measles vaccine
02

Targets

Enterovirus A71 capsid proteinMV (Measles virus)

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