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inactivated H1N1 vaccine (University of Rochester)
- Development stage
- Unknown
- Lead developer
- University of Rochester Medical Center
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
inactivated H1N1 vaccine (University of Rochester) is a monovalent inactivated influenza vaccine developed for the prevention of the 2009 pandemic H1N1 influenza virus. The vaccine was evaluated in clinical trials sponsored by the University of Rochester to investigate the immune response in different age groups and the impact of prior immunological priming. It consists of inactivated virus particles, typically the A/California/07/2009 (H1N1)pdm09 strain, and is administered via intramuscular injection. The primary mechanism of action involves the induction of hemagglutination inhibition (HAI) antibodies against the viral hemagglutinin protein, which prevents the virus from binding to and entering host cells.
- Other names
- inactivated H1N1 vaccine-University of Rochester-Influenza A (H1N1)novel H1N1 vaccine2009 H1N1 inactivated vaccineH1N1pdm09 vaccineH-1N1pdm09 vaccineH 1N1pdm09 vaccine
02
Targets
HA (Hemagglutinin)
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