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inactivated H5N1 whole-virion influenza vaccine
- Development stage
- Phase 1
- Lead developer
- Jilin Yatai Biological Pharmaceutical
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
The inactivated H5N1 whole-virion influenza vaccine is a viral vaccine developed for the prevention of avian influenza caused by the H5N1 subtype of the Influenza A virus. This specific formulation, developed by Jilin Yatai Biological Pharmaceutical, is produced using Vero cell culture technology rather than traditional egg-based methods. The vaccine contains the entire inactivated virus, which presents a broad array of viral antigens, including hemagglutinin (HA) and neuraminidase (NA), to the host immune system to stimulate protective antibody and cellular immune responses. It has been evaluated in Phase 1 clinical trials to assess its safety, tolerability, and preliminary immunogenicity in healthy adults.
- Other names
- inactivated H5N1 whole-virion vaccine (Vero cell)H5N1 whole-virion vaccineH-5N1 whole-virion vaccineH 5N1 whole-virion vaccine
02
Targets
M1 (Muscarinic acetylcholine receptor M1)NP (Taï Forest ebolavirus nucleoprotein)Influenza A virus RNA-directed RNA polymerase complexN1 NA (Influenza A neuraminidase N1)HA (Hemagglutinin)Neuraminidase
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