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The inactivated hepatitis A vaccine is a biological preparation used to induce active immunity against the hepatitis A virus (HAV). It typically consists of HAV particles (often the HM175 strain) grown in human cell culture, purified, and subsequently inactivated using formaldehyde. This specific clinical evaluation, associated with LiuZhou People's Hospital, focuses on the vaccine's immunogenicity and safety in HIV-infected individuals aged 1 to 50 years. Because HIV-infected patients may have a diminished immune response to standard vaccinations, this Phase IV trial assesses the effectiveness of a two-dose regimen administered at a six-month interval to ensure adequate seroconversion and long-term protection against hepatitis A infection.
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