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inactivated Lactobacillus reuteri LR-G100
- Development stage
- Unknown
- Lead developer
- BioGrowing
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral, Topical
01
Overview
Inactivated Lactobacillus reuteri LR-G100 is a postbiotic (paraprobiotic) ingredient developed by Bio-Growing, derived from a specific strain of Limosilactobacillus reuteri. The product consists of heat-killed bacterial cells that retain functional surface structures. Its primary mechanism of action in oral health involves the specific co-aggregation with Streptococcus mutans, the main causative agent of dental caries. By binding to S. mutans, LR-G100 prevents the pathogen from adhering to tooth surfaces and forming biofilms, allowing it to be rinsed away. Additionally, LR-G100 has demonstrated antagonistic activity against Helicobacter pylori, potentially through competitive exclusion and interference with adhesion in the gastric mucosa. As an inactivated strain, it offers formulation advantages over live probiotics, including stability in high-moisture environments like toothpaste and mouthwash.
- Other names
- 灭活罗伊氏粘液乳杆菌 LR-G100inactivated Limosilactobacillus reuteri LR-G100heat-killed Lactobacillus reuteri LR-G100LR-G100 postbioticLR-G-100 postbioticLR-G 100 postbiotic
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