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inactivated polio vaccine
- Development stage
- Unknown
- Lead developer
- Sanofi
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular, Subcutaneous
01
Overview
Inactivated polio vaccine (IPV) is a trivalent vaccine containing inactivated (killed) poliovirus strains of serotypes 1, 2, and 3. It is designed to induce systemic humoral immunity by stimulating the production of serum IgG antibodies that neutralize the virus, thereby preventing its spread to the central nervous system and protecting against paralytic poliomyelitis. In the clinical research context led by the University of Virginia in Matlab, Bangladesh, IPV is being evaluated in various routine immunization schedules alongside bivalent oral polio vaccine (bOPV). This research specifically assesses the impact of these regimens on the community transmission and fecal shedding of Sabin type 2 virus following the global withdrawal of trivalent oral polio vaccine (tOPV).
- Brand names
- Biovac IPV
- Other names
- Salk vaccineinactivated poliovirus vaccine
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