Drug intelligence / Profile preview

inactivated polio vaccine-PATH-influenza

Development stage
Unknown
Lead developer
PATH
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

inactivated polio vaccine-PATH-influenza refers to the specific set of vaccines—the seasonal trivalent inactivated influenza vaccine (TIV) and the inactivated polio vaccine (IPV)—utilized in a Phase 4 cluster-randomized clinical trial led by PATH in rural Senegal. The study was designed to evaluate the direct and indirect (herd) effectiveness of seasonal influenza vaccination in children aged 6 months to 10 years. In this trial framework, TIV served as the primary intervention to protect against three strains of seasonal influenza (typically A/H1N1, A/H3N2, and a B strain), while IPV was used as a control vaccine in the control clusters, providing protection against poliovirus types 1, 2, and 3. Both vaccines are inactivated (killed) virus platforms administered via injection to stimulate protective antibody responses without the risk of causing the diseases they target.

Other names
inactivated polio vaccineseasonal trivalent inactivated influenza vaccineIPVTIV
02

Targets

HA (Hemagglutinin)

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