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inactive patch-University of California, San Francisco-postoperative pain
- Development stage
- Unknown
- Lead developer
- University of California, San Francisco
- Administration
- Transdermal
01
Overview
The "inactive patch-University of California, San Francisco-postoperative pain" refers to a placebo control used in a Phase 4 clinical trial conducted by the University of California, San Francisco (UCSF). This inert transdermal patch was designed to match the appearance of a 25 mcg/hr fentanyl patch (Duragesic) to maintain blinding in a study evaluating the efficacy of prophylactic transdermal fentanyl for early postoperative pain management. The trial specifically targeted women undergoing mastectomy with immediate TRAM (transverse rectus abdominis myocutaneous) or DIEP (deep inferior epigastric perforator) flap reconstruction, comparing the patch's effectiveness as a bridge between epidural and oral analgesia. As a placebo, the patch contains no active pharmaceutical ingredients and serves as a comparator to assess the therapeutic effect and side profile of fentanyl in this surgical population.
- Other names
- Inactive patch
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