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INB-500

Development stage: Preclinical
Lead developer: IN8bio
Modality: CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, TCR-Engineered T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, iPSCs → Pluripotent Stem Cells → Stem Cell Therapies → Cell Therapies, Tumor-Infiltrating Lymphocytes (TILs) → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies

Overview

INB-500 is a gamma-delta induced pluripotent stem cell (iPSC) T cell therapy developed by IN8bio. It represents part of the company's DeltEx platform for producing expanded and modified gamma-delta T cells. The therapy is designed as an off-the-shelf allogeneic cell therapy product that could benefit from improved quality, quantity, cost and immediate availability compared to other cell therapy approaches. INB-500 is currently in preclinical development as part of IN8bio's pipeline of gamma-delta T cell therapies.

Other names: Gamma-delta iPSC T cells

Targets

MICB (Major histocompatibility complex class i-related protein B)MICA (Major histocompatibility complex class I-related protein A)

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