Indian Inst. of Technology Madras hNNMT compound 7b

Indian Inst. of Technology Madras hNNMT compound 7b: sourced facts only. name: "The MOA studies suggest that compound 7b functions as a bisubstrate competitive inhibitor of hNNMT, exhibiting competitive inhibition with respect to both SAM and quinoline, without altering Vmax." [PMID:40961781]; target: "The MOA studies suggest that compound 7b functions as a bisubstrate competitive inhibitor of hNNMT, exhibiting competitive inhibition with respect to both SAM and quinoline, without altering Vmax." [PMID:40961781]; developer: "Chemical Biology Laboratory, Bhupat and Jyoti Mehta School of Biosciences, Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600036, Tamil Nadu, India." [PMID:40961781]; stage: "Furthermore, cellular assays showed that compounds 7b, 7c, and 7d selectively suppressed the proliferation of U87 and PANC-1 cancer cells, and low cytotoxicity in HEK293 normal cell lines." [PMID:40961781]