indinavir + stavudine

Indinavir + stavudine is a combination of two antiretroviral drugs used primarily for the treatment of HIV-1 infection. Indinavir is a **HIV protease inhibitor** that blocks the viral enzyme protease, preventing viral replication[2][3]. Stavudine is a **nucleoside reverse transcriptase inhibitor (NRTI)** that inhibits HIV reverse transcriptase by competing with natural nucleosides, leading to termination of DNA chain elongation[1]. This combination is sometimes used as part of a multi-drug regimen for pediatric and adult patients with HIV, commonly in combination with a third agent such as didanosine, and is designed to suppress plasma HIV RNA and improve immunological status[1].

Other names

indinavir + stavudine