indium-111 bleomycin

**Indium-111 bleomycin** is a radiopharmaceutical drug formed by complexing the chemotherapy agent bleomycin with the radioisotope indium-111. It is investigated for use in radiochemotherapy, particularly in head and neck cancer, with clinical trials showing its potential effectiveness due to targeted tumor uptake and localized delivery of radiation. Its mechanism combines bleomycin’s DNA-cleaving antineoplastic action with the Auger electron emission from indium-111, resulting in enhanced tumor cell kill. Research also indicates potential synergy when combined with hyperthermia and suggests possible use for adjuvant Auger-electron therapy using other indium isotopes[1][3].

Other names

indium-111 bleomycinindium111 bleomycinindium 111 bleomycin111In-BLMC