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indocyanine green + methylene blue + technetium Tc 99m sulfur colloid

Development stage
Unknown
Lead developer
GE Healthcare
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intradermal, Subcutaneous, Peritumoral, Intratumoral, Subareolar
01

Overview

This is a combination of three different lymphatic tracers used for sentinel lymph node biopsy (SLNB) procedures. The combination includes indocyanine green (ICG), methylene blue (MB), and technetium Tc 99m sulfur colloid (Tc99m). When used together, these tracers provide enhanced visualization and identification of sentinel lymph nodes, particularly in early-stage breast cancer and other cancers. Studies have shown that combining these tracers results in very high identification rates (up to 100%) compared to using single tracers alone.

Other names
ICG + MB + Tc99mMethylene blue + ICG + Tc-99
02

Targets

VLDL (Very low-density lipoprotein)

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