indocyanine green lactosome

**Indocyanine green lactosome** is an experimental tumor-targeted nanomedicine in which the near-infrared dye and photosensitizer indocyanine green is incorporated into Lactosome polymeric micelles made from poly(L-lactic acid)-block-polysarcosine. Following intravenous administration, the particles circulate and preferentially accumulate in tumors through the enhanced permeability and retention effect, enabling near-infrared fluorescence visualization and localized light-triggered treatment. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/19525007/))\n\nUpon near-infrared laser irradiation, the indocyanine green payload mediates photodynamic and photothermal tumor-cell injury. Published preclinical studies have reported imaging and antitumor activity in hepatocellular carcinoma, gallbladder cancer, gastric-cancer peritoneal dissemination, spinal metastasis, and orthotopic neuroblastoma models. ([journals.plos.org](https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0183527))

Other names

ICG-LICG-lactosomeICG-loaded lactosomeindocyanine green lactosomeindocyanine green-loaded lactosome